How Often Do You Take Nootropics?

May. 29, 2024

The best time to take nootropics depends on their specific effects and your individual goals. Here’s a guide on when to take different types of nootropics:

Brain Health

Brain Health

Nootropics Best Taken During the Day

1. Stimulants

Examples: Modafinil, Adderall, Caffeine

Effects: Increase wakefulness, alertness, and focus.

Best Time: Morning or early afternoon.

Considerations: Taking stimulants later in the day can interfere with sleep.

2. Racetams

Examples: Piracetam, Aniracetam, Oxiracetam

Effects: Enhance cognitive functions such as memory, learning, and focus.

Best Time: Morning or early afternoon to avoid potential sleep disturbances.

Considerations: Some users may experience mild stimulation, so taking them earlier in the day is generally recommended.

3. L-Theanine and Caffeine

Effects: Improve focus and alertness without the jitteriness of caffeine alone.

Best Time: Morning or early afternoon.

Considerations: Provides a balanced boost in focus and calm, ideal for productive hours.



4. Bacopa Monnieri

Effects: Improves memory and reduces anxiety.

Best Time: Morning or with meals during the day.

Considerations: Bacopa has a cumulative effect, so consistent daily intake is more important than specific timing.

5. Ginkgo Biloba

Effects: Enhances memory and cognitive processing speed.

Best Time: Morning.

Considerations: Enhances blood flow and oxygen delivery to the brain, supporting daytime cognitive function.

Nootropics That Can Be Taken at Night

1. Adaptogens

Examples: Rhodiola Rosea, Ashwagandha

Effects: Reduce stress and improve overall cognitive function.

Best Time: Evening or before bed.

Considerations: These can promote relaxation and recovery from daytime stress.

2. L-Theanine (Alone)

Effects: Promotes relaxation without drowsiness.

Best Time: Evening or before bed.

Considerations: Can help ease anxiety and improve sleep quality.



3. Magnesium L-Threonate

Effects: Improves cognitive function and promotes relaxation.

Best Time: Evening.

Considerations: Supports brain health and can help improve sleep quality.

4. Melatonin

Effects: Regulates sleep-wake cycles.

Best Time: 30-60 minutes before bedtime.

Considerations: Aids in falling asleep and improving sleep quality.

5. Lion’s Mane Mushroom

Effects: Promotes nerve growth factor (NGF) production and overall brain health.

Best Time: Can be taken any time, but some prefer evening.

Considerations: Generally well-tolerated and can be taken in the evening without impacting sleep.

General Tips for Timing Nootropics

Personal Sensitivity: Pay attention to how you react to different nootropics. Adjust timing based on your sensitivity to their stimulating or calming effects.

Consistency: For nootropics that have cumulative effects (like Bacopa Monnieri or Lion’s Mane), consistent daily use is more important than the specific time of day.

Avoiding Interference with Sleep: Any nootropic with stimulating properties should be avoided in the late afternoon or evening to prevent sleep disturbances.

Stacking Nootropics: When combining nootropics, consider how they interact and choose a timing that maximizes their synergistic effects while minimizing side effects.


The optimal time to take nootropics depends on their specific effects and your individual goals. Stimulants and cognitive enhancers are generally best taken during the day to boost alertness and focus, while adaptogens and nootropics promoting relaxation and sleep are better suited for evening use. Always consider your personal response and adjust timing accordingly to achieve the best cognitive benefits without disrupting your sleep patterns.

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