Other Name: CDP choline, Cytosine Diphosphate Choline
Purity: ≥99%
CAS NO: 987-78-0
Formula: C14H26N4O11P2
Molecular Weight: 488.32
Certification: Kosher, Halal, FSSC 22000, GRAS
Brand: CitiCogni
Introduction
Citicoline, also known as CDP Choline, CDP-Choline, Citicholine, Cytidine 5'-Diphosphocholine, is a widely used ingredient in brain health products. It is well-known for its potential to support cognitive function, improve memory, enhance focus, and maintain optimal brain performance. At Witspower, we provide high-quality Citicoline Powder (CDP Choline Powder) for dietary supplements, nutraceuticals, and functional food products worldwide.
Citicoline (CDP Choline) is a naturally occurring compound in the human body, essential for neurotransmitter synthesis and neuronal membrane health. Originally used in Japan as a drug to support recovery after stroke, Citicoline has now become a popular ingredient in dietary supplements in the US and Europe, recognized for its cognitive benefits and brain health support.
Key aliases include:
Citicoline, CDP Choline, Citicholine, Cytidine 5-Diphosphocholine, Cytidine Diphosphate Choline, Cytidinediphosphocholine.
Applications: Citicoline is commonly used in products aimed at:
Cognitive enhancement
Memory support
Focus and concentration improvement
Healthy brain aging and neuroprotection
Citicoline Powder supports overall brain health by:
Promoting neuronal membrane integrity
Protecting brain cells from oxidative damage
Supporting neurogenesis (formation of new brain cells)
It is ideal for individuals and products targeting long-term cognitive performance and mental vitality.
CDP Choline Powder enhances memory by increasing acetylcholine production, a critical neurotransmitter for learning and memory formation. Clinical studies have shown improvements in short-term and long-term memory with regular Citicoline supplementation.
Citicoline has been demonstrated to improve attention span and reduce distractibility, making it a valuable ingredient for focus-oriented supplements, nootropic blends, and products targeting productivity.
By enhancing neuronal signaling and brain energy, Citicoline supports:
Faster information processing
Improved decision-making
Overall cognitive performance enhancement
At Witspower, quality is our top priority. Our Citicoline Powder undergoes strict quality control to ensure safety, consistency, and efficacy:
Advanced physical and chemical testing
Comprehensive microbial testing for bacteria, fungi, and viruses
Rigorous stability testing to maintain potency over time
Fully traceable production and raw material control
Every batch of CDP Choline Powder is tested to meet international standards, ensuring reliable performance for your formulations.
Traditional Citicoline production relies on chemical synthesis using coal tar or petroleum, which is costly and environmentally taxing.
At Witspower, we use advanced biosynthesis technology, empowering microbes and enzymatic fermentation to produce Citicoline naturally. This method is:
Environmentally friendly and sustainable
Cost-effective for large-scale production
Produces high-purity Citicoline Powder with minimal by-products
Highly efficient enzymatic hydrolysis
Stable conversion rate ≥90% per 6-hour production cycle
High purity with few by-products
Self-production of key material: Cytidylic Acid (CMP)
Cytidylic Acid (CMP) is the essential precursor for Citicoline. Witspower produces over 80% of the global Cytidylic Acid supply, allowing us to control quality, cost, and raw material availability. From Cytidine → Cytidylic Acid → Citicoline, every step is managed in-house, ensuring superior quality and competitive pricing.
Cognitive health supplements
Nootropic blends
Memory and focus support formulas
Healthy aging and brain protection products
Functional foods and beverages
Citicoline Powder is versatile, allowing for capsule, tablet, and powder formulations to meet different market needs.
High-quality, sustainable, and innovative
Advanced biosynthesis technology
Full control of raw materials and production
Backed by rigorous testing and quality assurance
Trusted supplier for global cognitive health products
For high-quality Citicoline Powder (CDP Choline Powder), technical support, and reliable supply for dietary supplements or cognitive health products, contact Witspower today. Partner with us to create safe, effective, and market-competitive formulations.
Specification
| Item | Specification |
| Appearance | White crystalline powder |
| Identification | Chemical reaction |
| The retention time of a major peak meets the requirements | |
| IR:consistent with the spectrum obtained with reference substance | |
| Loss on drying | ≤5.0% |
| pH | 2.5~3.5 |
| Ammonium | ≤0.05% |
| 5’-CMP | ≤1.0% |
| Free phosphoric acids | ≤0.1 |
| Assay(By HPLC) | 98%~102% |
| Purity(HPLC) | ≥99.0% |
| Heavy Metals | |
| Total | ≤10ppm |
| Lead(Pb) | ≤3.0ppm |
| Arsenic(As) | ≤2.0ppm |
| Cadmium(Cd) | ≤1.0ppm |
| Mercury(Hg) | ≤0.1ppm |
| Microbiological | |
| Total Plate Count | ≤1000cfu/g |
| Fungi count | ≤100cfu/g |
| Yeast &Mold | ≤100cfu/g |
| E.Coli. | Negative |
| Salmonella | Negative |
Application

Use As a Dietary Supplement
When taken as a supplement, citicoline is hydrolyzed into choline and cytidine in the intestine. Once these cross the blood–brain barrier it is reformed into citicoline by the rate-limiting enzyme in phosphatidylcholine synthesis, CTP-phosphocholine cytidylyltransferase. it can improve cognitive decline, improve memory for middle-aged and elderly people, prevent Alzheimer's, prevent Alzheimer's, Parkinson's, etc.

Use in Functional Food and Beverage
When it is used in food industry, it usually exists in the form of energy drinks in the market. It can improve Concentration, Concentration, Use by Young People, Adults.

Use in Pharmaceutical
In some countries, Citicoline can be used in pharmacetical area, It can be treatment of stroke, brain dysfunction caused by accidents, etc., commonly used in injections, oral drugs.
Logistics Tips
North America area:
Ship from LA warehouse
Other countries or areas:
Ship from China Production Base
Express by DHL or Fedex
Under 100kg, 4-6days
Door to door service, easy to pick up
By Air shipping
100KG-1000KG, 5-7 days
Airport to airport service, professional clearance broker needed.
By Sea shipping
Over 300KG, Around 30days
Port to port service, professional clearance broker needed.

Our Service
1. Free sample is available for your evaluation
2. Outstanding quality assurance: COA, OU kosher certificate, Halal certificate, FSSC 22000 Quality Management Certificate, US-GRAS.
3. 30 days unconditional refund if unqualified.
4. 24 hours online to ensure timely responds.
Our company boasts several advantages that make us stand out in the market:
1. High Purity Products: We are committed to providing products of the highest quality. Our products have a purity level of 98%-99%, ensuring that our customers receive the most effective and purest form of our product.
2. Cognitive Health Focus: We specialize in cognitive health products, designed to improve cognitive function and memory. Our products have been shown to be effective in managing senile diseases and improving overall brain health.
3. Technological Advantages: Our company uses a unique and innovative approach to manufacture our products. Unlike traditional chemical processes used by other manufacturers, we use fermentation technology to produce our Citicoline products.
4. Strong Factory Capacity: Our manufacturing facility has a factory capacity of 500 tons of nucleotide series products including citicoline, making us one of the largest producers of Citicoline in the market.
5. Third-Party Qualification Certification: We have a complete set of third-party qualification certifications, which ensures the quality and safety of our products.
6. US Warehouse: We have an overseas warehouse located in the United States, allowing us to deliver our products within 2 days to our customers, ensuring timely and efficient delivery.
In summary, our high-purity products, focus on brain health, technological advantages, strong factory capacity, third-party qualification certification, and efficient US warehouse make us an excellent choice for those seeking quality and effective Citicoline products.
Witspower is a famous brand in the field of cognitive health, dedicated to providing innovative and effective solutions to help people maintain and enhance their cognitive health. Our flagship product, Citicoline, is a powerful nootropic that has been shown to improve memory, focus, and mental clarity.
At Witspower, we have developed a unique form of Citicoline that is highly bioavailable and optimized for maximum cognitive benefits. Our product is backed by extensive scientific research and clinical trials, which have shown that Citicoline can improve cognitive function in both healthy individuals and those with cognitive decline.
Our mission at Witspower is to help people optimize their cognitive function and achieve their full potential. We believe that Citicoline is a game-changer in the field of cognitive health, and we are committed to making it accessible to everyone. Whether you are older or younger, an athletes, or an ordinary consumer looking to maintain your cognitive health, Witspower has the solution for you.
Join us on our mission to unlock the full potential of your brain with Citicoline from Witspower.

Quick Links
Tel: +1 213 554 2947
E-mail: info@witspower.com
WhatsApp: +86 186 2946 5189
Skype: howey8825
Add: 895 S Rockefeller Ave, Suite 101, Ontario, CA91761