Other Name: CDP choline, Cytosine Diphosphate Choline
Purity: ≥99%
CAS NO: 987-78-0
Formula: C14H26N4O11P2
Molecular Weight: 488.32
Certification: Kosher, Halal, FSSC 22000, GRAS
Brand: CitiCogni
Introduction
Citicoline, also known as CDP Choline, CDP-Choline, Citicholine, Cytidine 5'-Diphosphocholine, is a widely used ingredient in brain health products. It is well-known for its potential to support cognitive function, improve memory, enhance focus, and maintain optimal brain performance. At Witspower, we provide high-quality Citicoline Powder (CDP Choline Powder) for dietary supplements, nutraceuticals, and functional food products worldwide.
Citicoline (CDP Choline) is a naturally occurring compound in the human body, essential for neurotransmitter synthesis and neuronal membrane health. Originally used in Japan as a drug to support recovery after stroke, Citicoline has now become a popular ingredient in dietary supplements in the US and Europe, recognized for its cognitive benefits and brain health support.
Key aliases include:
Citicoline, CDP Choline, Citicholine, Cytidine 5-Diphosphocholine, Cytidine Diphosphate Choline, Cytidinediphosphocholine.
Applications: Citicoline is commonly used in products aimed at:
Cognitive enhancement
Memory support
Focus and concentration improvement
Healthy brain aging and neuroprotection
Specification
| Item | Specification |
| Appearance | White crystalline powder |
| Identification | Chemical reaction |
| The retention time of a major peak meets the requirements | |
| IR:consistent with the spectrum obtained with reference substance | |
| Loss on drying | ≤5.0% |
| pH | 2.5~3.5 |
| Ammonium | ≤0.05% |
| 5’-CMP | ≤1.0% |
| Free phosphoric acids | ≤0.1 |
| Assay(By HPLC) | 98%~102% |
| Purity(HPLC) | ≥99.0% |
| Heavy Metals | |
| Total | ≤10ppm |
| Lead(Pb) | ≤3.0ppm |
| Arsenic(As) | ≤2.0ppm |
| Cadmium(Cd) | ≤1.0ppm |
| Mercury(Hg) | ≤0.1ppm |
| Microbiological | |
| Total Plate Count | ≤1000cfu/g |
| Fungi count | ≤100cfu/g |
| Yeast &Mold | ≤100cfu/g |
| E.Coli. | Negative |
| Salmonella | Negative |
Application
Use As a Dietary Supplement
When taken as a supplement, citicoline is hydrolyzed into choline and cytidine in the intestine. Once these cross the blood–brain barrier it is reformed into citicoline by the rate-limiting enzyme in phosphatidylcholine synthesis, CTP-phosphocholine cytidylyltransferase. it can improve cognitive decline, improve memory for middle-aged and elderly people, prevent Alzheimer's, prevent Alzheimer's, Parkinson's, etc.
Use in Functional Food and Beverage
When it is used in food industry, it usually exists in the form of energy drinks in the market. It can improve Concentration, Concentration, Use by Young People, Adults.
Use in Pharmaceutical
In some countries, Citicoline can be used in pharmacetical area, It can be treatment of stroke, brain dysfunction caused by accidents, etc., commonly used in injections, oral drugs.
Logistics Tips
North America area：
Ship from LA warehouse
Other countries or areas:
Ship from China Production Base
Express by DHL or Fedex
Under 100kg, 4-6days
Door to door service, easy to pick up
By Air shipping
100KG-1000KG, 5-7 days
Airport to airport service, professional clearance broker needed.
By Sea shipping
Over 300KG, Around 30days
Port to port service, professional clearance broker needed.
Our Service
1. Free sample is available for your evaluation
2. Outstanding quality assurance: COA, OU kosher certificate, Halal certificate, FSSC 22000 Quality Management Certificate, US-GRAS.
3. 30 days unconditional refund if unqualified.
4. 24 hours online to ensure timely responds.
Citicoline Powder supports overall brain health by:
Promoting neuronal membrane integrity
Protecting brain cells from oxidative damage
Supporting neurogenesis (formation of new brain cells)
It is ideal for individuals and products targeting long-term cognitive performance and mental vitality.
CDP Choline Powder enhances memory by increasing acetylcholine production, a critical neurotransmitter for learning and memory formation. Clinical studies have shown improvements in short-term and long-term memory with regular Citicoline supplementation.
Citicoline has been demonstrated to improve attention span and reduce distractibility, making it a valuable ingredient for focus-oriented supplements, nootropic blends, and products targeting productivity.
By enhancing neuronal signaling and brain energy, Citicoline supports:
Faster information processing
Improved decision-making
Overall cognitive performance enhancement
At Witspower, quality is our top priority. Our Citicoline Powder undergoes strict quality control to ensure safety, consistency, and efficacy:
Advanced physical and chemical testing
Comprehensive microbial testing for bacteria, fungi, and viruses
Rigorous stability testing to maintain potency over time
Fully traceable production and raw material control
Every batch of CDP Choline Powder is tested to meet international standards, ensuring reliable performance for your formulations.
Traditional Citicoline production relies on chemical synthesis using coal tar or petroleum, which is costly and environmentally taxing.
At Witspower, we use advanced biosynthesis technology, empowering microbes and enzymatic fermentation to produce Citicoline naturally. This method is:
Environmentally friendly and sustainable
Cost-effective for large-scale production
Produces high-purity Citicoline Powder with minimal by-products
Highly efficient enzymatic hydrolysis
Stable conversion rate ≥90% per 6-hour production cycle
High purity with few by-products
Self-production of key material: Cytidylic Acid (CMP)
Cytidylic Acid (CMP) is the essential precursor for Citicoline. Witspower produces over 80% of the global Cytidylic Acid supply, allowing us to control quality, cost, and raw material availability. From Cytidine → Cytidylic Acid → Citicoline, every step is managed in-house, ensuring superior quality and competitive pricing.
Cognitive health supplements
Nootropic blends
Memory and focus support formulas
Healthy aging and brain protection products
Functional foods and beverages
Citicoline Powder is versatile, allowing for capsule, tablet, and powder formulations to meet different market needs.
High-quality, sustainable, and innovative
Advanced biosynthesis technology
Full control of raw materials and production
Backed by rigorous testing and quality assurance
Trusted supplier for global cognitive health products
For high-quality Citicoline Powder (CDP Choline Powder), technical support, and reliable supply for dietary supplements or cognitive health products, contact Witspower today. Partner with us to create safe, effective, and market-competitive formulations.
Quick Links
Tel: +1 213 554 2947
E-mail: info@witspower.com
WhatsApp: +86 186 2946 5189
Skype: howey8825
Add: 895 S Rockefeller Ave, Suite 101, Ontario, CA91761
