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How Phosphatidylserine Supports Cognitive Function

Jul. 22, 2025

Phosphatidylserine is a phospholipid essential for maintaining healthy brain cell membranes and ensuring efficient nerve signal transmission. As a key ingredient in cognitive support supplements, Phosphatidylserine has become a preferred choice among B2B buyers developing functional food and nutraceutical solutions. If you're sourcing premium-grade Phosphatidylserine, understanding its mode of action, formulation potential, and commercial viability is crucial. You can learn more about our PS offering on Witspower’s Phosphatidylserine Product Center.


Mechanisms of Action—How Phosphatidylserine Works in the Brain

Your product's success depends on active ingredients with verified physiological functions. Phosphatidylserine contributes to optimal neuronal function by preserving membrane fluidity, enabling faster and more accurate neurotransmission. It is known to support key neurotransmitters like acetylcholine, dopamine, and norepinephrine—critical for memory, learning, and mood regulation. Additionally, Phosphatidylserine modulates cortisol levels, helping mitigate cognitive fatigue and stress-related memory loss. These mechanisms make it an indispensable component in brain health formulations.


Scientific Evidence Behind Phosphatidylserine and Cognitive Health

Multiple clinical trials support the efficacy of Phosphatidylserine in age-related cognitive decline, ADHD, and stress-induced cognitive impairment. For instance, elderly subjects consuming 300mg/day over 12 weeks demonstrated improved verbal recall and memory retention. In children with attention-related challenges, supplementation resulted in better focus and task performance. These findings provide a scientific foundation for including Phosphatidylserine in cognitive health products targeting diverse age groups.


Applications in Functional Food and Nutraceutical Products

Whether you are developing capsules, tablets, or powdered drink blends, Phosphatidylserine offers formulation versatility. Its compatibility with DHA, Ginkgo Biloba, and B-vitamins enhances synergistic effects for brain performance. In softgel formulations, emulsification and encapsulation technologies help retain PS bioavailability. From a marketing perspective, claims such as "memory support" and "brain performance" linked with Phosphatidylserine provide clear value in competitive markets.


Choosing the Right Phosphatidylserine for Your Product Line

You should carefully evaluate the source (soy vs. sunflower), concentration (20%-70%), and physical form (powder vs. granular) based on your application. Soy-derived PS is widely used, but sunflower PS is gaining traction for non-GMO and allergen-free claims. Regulatory compliance, particularly with EFSA, FDA, and China’s NHC, should also guide your decision. At Witspower, we help you match the correct specification to your product's positioning and target market.


Why B2B Partners Choose Witspower Phosphatidylserine

Witspower offers a full range of Phosphatidylserine materials, including soy and sunflower-based variants, tailored for bulk purchase and OEM/ODM services. With scalable production, strict quality control, and comprehensive certification support, we enable your team to develop stable, high-performance brain health products. Explore our full ingredient range on the Witspower Phosphatidylserine Product Center.


Technical Support and Custom Formulation Services

As your technical partner, we provide support for ingredient selection, formula optimization, and market-specific documentation. Our team assists you with CoA, MSDS, TDS, and regulatory filings to speed up time-to-market. For formulation or OEM inquiries, contact us directly or browse our ingredient center for complementary nootropic solutions.


Conclusion & CTA: Start Your Cognitive Health Product with Witspower Today

Phosphatidylserine is a scientifically supported, commercially scalable, and formulation-flexible ingredient for your next-generation cognitive health product. Partnering with Witspower gives you access to top-tier raw materials and full-cycle B2B support. Ready to enhance your product line?

Contact Witspower Now to request technical documentation or product samples.

Or view Phosphatidylserine specifications and sourcing details.

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